Thalamotomy and caudatotomy with the Gamma Knife as a treatment for parkinsonism with a comment on lesion sizes
| Autor: | O. Schröttner, P. Pachatz, C.L. Ojakangas, Gerhard Friehs, E. Ott, G. Pencil |
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| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Thalamus Caudate nucleus Gamma knife Radiosurgery Lesion Central nervous system disease medicine Humans Aged business.industry Thalamotomy Parkinsonism Parkinson Disease Middle Aged medicine.disease Surgery Thalamic Nuclei Neurology (clinical) medicine.symptom Caudate Nucleus Nuclear medicine business Follow-Up Studies |
| Zdroj: | Stereotactic and functional neurosurgery. 64 |
| ISSN: | 1011-6125 |
| Popis: | Radiosurgery with the Gamma Knife was performed in 12 patients with parkinsonism. In 9 patients small lesions were created in the head of the caudate nucleus bilaterally. Two patients underwent radiosurgical thalamotomy, and 1 patient was treated with caudatotomy and thalamotomy. After a follow-up period of 1-12 months, 9 patients of the caudatotomy group and all patients with thalamotomies showed clear benefit. There was no complication or side effect that could be related to the treatment. Pre- and postoperative testing was performed with the Unified Parkinson Rating Scale and with objective motor tasks. Caudatotomy proved to be an effective treatment for bradykinesia and rigidity, while tremor was ameliorated by thalamotomy. Functional neurosurgery with the Gamma Knife would seem to be a good alternative to open procedures with low morbidity and no mortality. Advantages and drawbacks of radiosurgical techniques for the treatment of parkinsonism are discussed. |
| Databáze: | OpenAIRE |
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