Pulmonary embolism: segmental appearance of perfusion lung scan defects correlates with successful response to thrombolytic therapy
| Autor: | Samuel Z. Goldhaber, John Parker, D E Drum, S S Tumeh, J S Nagel |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Response to therapy Ventilation/perfusion ratio FAVORABLE RESPONSE Ventilation-Perfusion Ratio Humans Medicine Thrombolytic Therapy Radiology Nuclear Medicine and imaging Radionuclide imaging Radionuclide Imaging Lung Technetium Tc 99m Aggregated Albumin Probability business.industry Lung scan Middle Aged medicine.disease Urokinase-Type Plasminogen Activator Recombinant Proteins Pulmonary embolism Tissue Plasminogen Activator Female Radiology Pulmonary Embolism business Perfusion |
| Zdroj: | Radiology. 174:483-486 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.174.2.2104990 |
| Popis: | Lung scan data from a series of 45 patients receiving thrombolytic therapy were reviewed to determine if any pattern on the pretherapy perfusion lung scans could be identified that predicted response to therapy. A segmental appearance on the pretherapy scans (complete or nearly complete absence of perfusion in a whole segment or a very large subsegment) was correlated with the amount of improvement in perfusion on lung scans obtained 24 hours after the start of thrombolytic therapy. As a group, patients with a segmental appearance on the pretherapy lung scans had more improvement in the perfusion reduction score than patients with a nonsegmental appearance (P less than .005). However, the correlation between segmental appearance and a favorable response to thrombolytic therapy was not strong enough to allow use of this appearance in the selection of patients for therapy. |
| Databáze: | OpenAIRE |
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