Overview in the clinical management of patients with seronegative villous atrophy
| Autor: | Annalisa Schiepatti, David S Sanders, Martina Zuffada, Federico Biagi, Ombretta Luinetti, Adam Iraqi |
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| Rok vydání: | 2018 |
| Předmět: |
Pediatrics
medicine.medical_specialty Diet therapy Context (language use) Coeliac disease Gliadin Autoimmune Diseases Diagnosis Differential 03 medical and health sciences Diet Gluten-Free 0302 clinical medicine Atrophy Intestinal mucosa medicine Humans Villous atrophy Intestinal Mucosa Autoantibodies Hepatology business.industry Gastroenterology medicine.disease Celiac Disease 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Gluten free Differential diagnosis business Biomarkers |
| Zdroj: | European journal of gastroenterologyhepatology. 31(4) |
| ISSN: | 1473-5687 |
| Popis: | Differential diagnosis and management of enteropathies found in the context of seronegative villous atrophy (VA) are still a clinical challenge. Although seronegative coeliac disease may be the most frequent cause of serology-negative VA, other conditions must be taken into account in the differential diagnosis of seronegative VA. The rarity of these enteropathies with frequent overlapping of histological features may result in misclassification of such patients as affected by a seronegative or a refractory form of coeliac disease with consequent inappropriate treatments and long-term morbidity. The aim of this review is to summarize the current knowledge and to provide an evidence base and practical algorithmic approach for the investigation and management of seronegative VA. |
| Databáze: | OpenAIRE |
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