Ingestion of medium chain fatty acids by lactating dairy cows increases concentrations of plasma ghrelin
| Autor: | Hiroyuki Shingu, Taketo Obitsu, Yoshihisa Hasegawa, Kenji Kangawa, Toshihisa Sugino, Kohzo Taniguchi, Rika Fukumori, Naoko Moriya, H. Kobayashi, Masayasu Kojima, Shiro Kushibiki |
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| Rok vydání: | 2013 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Metabolite Fatty Acids Nonesterified chemistry.chemical_compound Endocrinology Food Animals Glucagon-Like Peptide 1 Internal medicine medicine Animals Insulin Lactation Ingestion Dry matter Lactose Morning Cross-Over Studies 3-Hydroxybutyric Acid Chemistry Fatty Acids food and beverages Dietary Fats Crossover study Ghrelin Diet Milk Dietary Supplements Cattle Female Animal Science and Zoology Hormone |
| Zdroj: | Domestic Animal Endocrinology. 45:216-223 |
| ISSN: | 0739-7240 |
| DOI: | 10.1016/j.domaniend.2013.09.005 |
| Popis: | The purpose of this study was to elucidate the effects of medium-chain fatty acids (MCFAs) on plasma ghrelin concentration in lactating dairy cows. Five early-lactating Holstein cows were randomly assigned to 2 dietary treatments in a crossover design with 2-wk periods. Treatments consisted of diets supplemented or not (control) with calcium salts of MCFAs (MCFA-Ca; 1.5% dry matter). Plasma hormone and metabolite concentrations in blood samples taken from the jugular vein were measured on the morning of feeding on day 14 of each period. Dry matter intake, milk protein, and lactose content of cows fed the MCFA-Ca diet were decreased compared with controls, but with no change in milk yield. Plasma ghrelin concentrations were higher in cows fed the MCFA-Ca diet; however, no significant effect was found on glucagon-like peptide-1 concentrations in plasma. Plasma insulin concentrations decreased, but plasma glucagon concentrations remained unchanged in cows fed the MCFA-Ca diet. The concentrations of nonesterified FAs, total cholesterol, and β-hydroxybutyrate in plasma increased in these cows. In conclusion, dietary MCFAs increase the plasma ghrelin concentrations in lactating dairy cows. |
| Databáze: | OpenAIRE |
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