Daily Practice of Mechanical Ventilation and Weaning in Turkish PICUs: A Multicenter Prospective Survey
| Autor: | Mehmet Bosnak, Demet Demirkol, Utku Karaarslan, Hasan Ağın, Mehmet Davutoglu, Feyza Girgin Inceköy, Özden Özgür Horoz, Tahir Dalkıran, Ayse Berna Anil, Agop Çıtak, Deniz Ozel, Tanıl Kendirli, Şükrü Paksu, Nazik Yener, Dinçer Yildiztaş, Ener Cagri Dinleyici, Güntülü Şık, Tolga Köroğlu, Pinar Yazci, Fatih Aygün, Ayhan Yaman, Oguz Dursun, Esra Şevketoğlu, Nilüfer Öztürk, Hakan Tekgüç, Bülent Karapinar, Seher Erdoğan, Fulya Kamit Can, Rana İşgüder |
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| Přispěvatelé: | Ondokuz Mayıs Üniversitesi, Ege Üniversitesi |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
extubation Turkey pediatrics intensive care units medicine.medical_treatment positive pressure ventilation mechanical ventilation 030204 cardiovascular system & hematology Intensive Care Units Pediatric Critical Care and Intensive Care Medicine Cohort Studies Sepsis 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires medicine Risk of mortality Humans Intubation Weaning Prospective Studies Child Mechanical ventilation business.industry weaning Infant 030208 emergency & critical care medicine medicine.disease Respiration Artificial Pediatrics Perinatology and Child Health Emergency medicine Cohort Observational study business Ventilator Weaning Cohort study |
| Popis: | Objectives: To investigate conventional mechanical ventilation weaning characteristics of patients requiring conventional mechanical ventilation support for greater than 48 hours within the PICU. Design: the prospective observational multicenter cohort study was conducted at 15 hospitals. Data were being collected from November 2013 to June 2014, with two designated researchers from each center responsible for follow-up and data entry. Setting: Fifteen tertiary PICUs in Turkey. Patients: Patients between 1 month and 18 years old requiring conventional mechanical ventilation for greater than 48 hours were included. A single-center was not permitted to surpass 20% of the total sample size. Patients with no plans for conventional mechanical ventilation weaning were excluded. Interventions: Conventional mechanical ventilation Measurements and Main Results: Pertinent variables included PICU and patient demographics, including clinical data, chronic diseases, comorbid conditions, and reasons for intubation. Conventional mechanical ventilation mode and weaning data were characterized by daily ventilator parameters and blood gases. Patients were monitored until hospital discharge. of the 410 recruited patients, 320 were included for analyses. A diagnosis of sepsis requiring intubation and high initial peak inspiratory pressures correlated with a longer weaning period (mean, 3.65 vs 1.05-2.17 d; p < 0.001). Conversely, age, admission Pediatric Risk of Mortality III scores, days of conventional mechanical ventilation before weaning, ventilator mode, and chronic disease were not related to weaning duration. Conclusions: Pediatric patients requiring conventional mechanical ventilation with a diagnosis of sepsis and high initial peak inspiratory pressures may require longer conventional mechanical ventilation weaning prior to extubation. Causative factors and optimal weaning for this cohort needs further consideration. National Institutes of HealthUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA Drs. Sik, Yaman, and Kendirli disclosed government work. Drs. Yaman and Davutoglu received support for article research from the National Institutes of Health. the remaining authors have disclosed that they do not have any potential conflicts of interest. |
| Databáze: | OpenAIRE |
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