T-CELL LYMPHOCYTIC LEUKEMIA IN A FALLOW DEER (DAMA DAMA)
| Autor: | Daniel S. Bradway, Wm. Kirk Suedmeyer, Michael M. Garner, Brian G. Stockinger, Matti Kiupel, Charlotte Hollinger |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Leukemia T-Cell Lymphocytosis Anemia Population Anti-Inflammatory Agents Penicillin G Procaine Biology Dexamethasone Andrology medicine Animals Leukocytosis education education.field_of_study General Veterinary medicine.diagnostic_test Deer Epizootic hemorrhagic disease virus Complete blood count General Medicine medicine.disease Lactulose Anti-Bacterial Agents Leukemia medicine.anatomical_structure Fluid Therapy Female Animal Science and Zoology Bone marrow medicine.symptom |
| Zdroj: | Journal of Zoo and Wildlife Medicine. 46:580-582 |
| ISSN: | 1937-2825 1042-7260 |
| Popis: | A 17-yr-old female fallow deer presented with ataxia, inappetence, decreased fecal output, and decreased mentation. A complete blood count demonstrated leukocytosis (24.1×10(3)/μl, n=1.16-7.38×10(3)/μl), characterized by lymphocytosis (22.89×10(3)/μl, n=0.18-3.65×10(3)/μl), anemia (packed cell volume 20%, n=29.0-55.8%), decreased red blood cell count (4.1×10(3)/μl, n=6.86-14.72×10(3)/μl), and decreased hemoglobin (7.5 g/dl, n=9.4-19.2 g/dl). Numerous mature, well-differentiated lymphocytes were noted on the blood film. Despite treatment and clinical improvement, the decision was made to euthanize the deer. Histopathology identified a monomorphic population of CD3 positive, CD79a negative small lymphocytes replacing most of the hematopoietic tissue in the bone marrow without evidence of tissue invasion. Results of viral screening were negative. |
| Databáze: | OpenAIRE |
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