Ozone against Pseudomonas aeruginosa biofilms in contact lenses storage cases
| Autor: | Sandra Maria Oliveira Morais Veiga, Paula Anatália Pereira Bredarioli, Fabrício Damasceno Leandro, Carla Benedini Ribeiro Jorge Ferreira, Josidel Conceição Oliver, Amanda Latercia Tranches Dias |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Ozone
lcsh:Arctic medicine. Tropical medicine Contact Lenses lcsh:RC955-962 Disinfectant 030231 tropical medicine Colony Count Microbial Microbial Sensitivity Tests Brief Communication medicine.disease_cause Microbiology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Ultrasound medicine Decontamination Pseudomonas aeruginosa Ocular Infections Chlorhexidine Biofilm Water Multipurpose solutions Ozonized water Contact lens solutions chemistry Biofilms Colony count Contact Lens Solutions Disinfectants medicine.drug |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo, Vol 61, Iss 0 (2019) Revista do Instituto de Medicina Tropical de São Paulo; Vol. 61 (2019); e23 Revista do Instituto de Medicina Tropical de São Paulo; v. 61 (2019); e23 Revista do Instituto de Medicina Tropical de São Paulo Instituto de Medicina Tropical (IMT) instacron:IMT Revista do Instituto de Medicina Tropical de São Paulo, Volume: 61, Article number: e23, Published: 18 APR 2019 |
| ISSN: | 1678-9946 0036-4665 |
| Popis: | Pseudomonas aeruginosa is associated with ocular infections such as keratitis. Multipurpose contact lens solutions can be used for washing, disinfection and storage of contact lenses, however, P. aeruginosa biofilm disinfection by this method is unsatisfactory. The present study aimed to investigate the effectiveness of ozonated water in reducing P. aeruginosa colony count. Lenses kept in storage cases were contaminated with P. aeruginosa and disinfected using ozonized water, chlorhexidine, ultrasound and multipurpose solutions. The multipurpose solutions and ultrasound methods reduced colony count from 1.17 to 1.63 log10 CFU/cm2 (92.93% to 97.31%), respectively, of P. aeruginosa biofilm cell viability when compared to the positive control. Both, ozonated water and chlorhexidine showed 7.42 log reduction in the number of viable cells of P. aeruginosa biofilm. As compared to chlorhexidine, ozonized water did not depose any known toxic residues, so that we recommend it as an alternative disinfectant solution for contact lenses storage cases. |
| Databáze: | OpenAIRE |
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