[Evaluation of diagnostic criteria of heart failure in patients with atrial fibrillation and chronic obstructive pulmonary disease]
| Autor: | V. P. Terentyev, V. A. Safronenko, A I Chesnikova, O. E Kolomatskaya, T A Dzyurich |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Pulmonary disease 030204 cardiovascular system & hematology Contractility 03 medical and health sciences Pulmonary Disease Chronic Obstructive 0302 clinical medicine Internal medicine Atrial Fibrillation Natriuretic Peptide Brain medicine Natriuretic peptide Humans In patient Heart Atria Heart Failure COPD business.industry Atrial fibrillation medicine.disease Peptide Fragments medicine.anatomical_structure 030228 respiratory system Ventricle Heart failure Cardiology Cardiology and Cardiovascular Medicine business Atrial Natriuretic Factor |
| Zdroj: | Kardiologiia. 59(10S) |
| ISSN: | 0022-9040 |
| Popis: | Aim. Assess the diagnostic significance of markers of heart failure, to identify the features of clinical symptoms and structural and functional remodeling of the left and right heart in patients with chronic heart failure (CHF) in combination with atrial fibrillation (AF) and chronic obstructive pulmonary disease (COPD). Materials and methods. groups of patients were formed: group 1 – patients with COPD without cardiovascular diseases (n=28), group 2 – patients with CHF and COPD without AF (n=30), group 3 – patients with CHF and AF without COPD (n=33), group 4 (main) – patients with CHF, AF and COPD (n=29). Patients were evaluated for clinical symptoms, 6-minute walk test, echocardiographic study, determined the concentration of natriuretic peptides (NUP): N-terminal fragment of the precursor of cerebral NUP (NT-proBNP) and mid-regional pro-atrial NUP (MR-proANP). Results. In patients with CHF on the background of AF and COPD, a higher score of the severity of clinical symptoms was established in comparison with the 3rd group (pConclusion. In patients with CHF, AF and COPD, more pronounced clinical symptoms are caused by chronic bronchial obstruction. Pathogenetic features of left and right heart remodeling in patients with CHF on the background of AF and COPD were revealed. For the early detection of HF in patients with AF the greatest diagnostic importance is the determination of the level of MR-proANP, however, in patients with combined AF and COPD the most informative is the determination of the concentration of NT-proBNP. |
| Databáze: | OpenAIRE |
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