The aggregation behavior of trimetazidine hydrochloride in aqueous solutions at different temperatures
Autor: | Lütfi Genç |
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Přispěvatelé: | Anadolu Üniversitesi, Eczacılık Fakültesi, Farmasötik Teknoloji Anabilim Dalı, Genç, Lütfi |
Rok vydání: | 2015 |
Předmět: |
Molality
Aqueous solution Chemistry Trimetazidine Thermodynamics Conductivity Condensed Matter Physics Micelle Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Cmc Electrical resistivity and conductivity Critical micelle concentration Trimetazidine hydrochloride Materials Chemistry Isentropic Compressibility Ultrasonic sensor Physical and Theoretical Chemistry Isentropic Apparent Molal Compressibility Spectroscopy |
Zdroj: | Journal of Molecular Liquids. 208:165-169 |
ISSN: | 0167-7322 |
DOI: | 10.1016/j.molliq.2015.04.038 |
Popis: | WOS: 000357230700026 The aggregation behavior of trimetazidine hydrochloride (TMZ HCl) in aqueous solutions has been investigated by electrical conductivity, ultrasonic speed and density measurements in the temperature ranges from 298.15 to 313.15 K, at 5 K intervals. The critical micelle concentration (cmc) values of TMZ HCl in aqueous solutions were evaluated by using conductivity measurements. The conductivity values of the solutions have been employed to determine the critical micelle concentrations by applying the Williams definition and the Phillips method. Apparent molal volumes and isentropic compressibility values have also been calculated from the experimental density and ultrasonic speed data. The interionic interactions and hydrophilic-hydrophobic and hydrophobic-hydrophobic group interactions on TMZ HCl aqueous solutions have also been studied at different temperatures by using ultrasonic speed, density and conductivity measurements, respectively |
Databáze: | OpenAIRE |
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