Timing should no Longer be an Obstacle to Oocyte Cryopreservation in Patients with Cancer
| Autor: | Enrico Papaleo, Rossella Masciangelo, Veronica Sarais, Valentina E. Di Mattei, Veronica Giorgione, Massimo Candiani, Giorgia Mangili, Roberta Nale, Laura Privitera, Letizia Carnelli, Cristina Sigismondi |
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| Přispěvatelé: | Mangili, Giorgia, Papaleo, Enrico, Sigismondi, Cristina, Masciangelo, Rossella, Sarais, Veronica, Giorgione, Veronica, Nale, Roberta, Privitera, Laura, Carnelli, Letizia, DI MATTEI, Valentina, Candiani, Massimo |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Counseling Infertility Oocyte Cancer Research medicine.medical_specialty Time Factors Adolescent Time Factor media_common.quotation_subject Oncofertility Unit Fertility Oncofertility Young Adult 03 medical and health sciences 0302 clinical medicine Ovulation Induction Retrospective Studie Neoplasms Humans Medicine In patient Fertility preservation Retrospective Studies media_common Cryopreservation Gynecology 030219 obstetrics & reproductive medicine business.industry Medicine (all) Fertility Preservation Cancer General Medicine Oocyte cryopreservation Middle Aged medicine.disease Oncology Anticancer treatment 030220 oncology & carcinogenesis Oocytes Neoplasm Female business Infertility Female Human |
| Zdroj: | Tumori Journal. 103:182-186 |
| ISSN: | 2038-2529 0300-8916 |
| DOI: | 10.5301/tj.5000586 |
| Popis: | Purpose Anticancer treatment-related infertility is preventable with oocyte cryopreservation, but this is often not considered a relevant issue, due to lack of knowledge and time. The aim of this study is to prove that adequate organization of an Oncofertility Unit and the use of new protocols for controlled ovarian stimulation (COS) can reduce the time required by the procedure, encouraging consultants and patients to preserve fertility before gonadotoxic treatments. Methods A total of 125 patients diagnosed with malignant tumors were referred to the Oncofertility Unit of San Raffaele Hospital: 52 patients between April 2011 and October 2013 and 73 patients between October 2013 and November 2015. The 2 periods differ in office organization and type of COS protocol used. Results Between the 2 periods, a reduction in the mean number of days required from first counseling to the initiation (6.45 ± 1.058 vs 1.61 ± 0.228) and the end of the COS (17.83 ± 1.227 vs 13.70 ± 0.393) was observed (pConclusions Renewed organization of the Oncofertility Unit and the newest random-start COS protocol allowed us to shorten the time for oocyte cryopreservation and start anticancer treatment on time. |
| Databáze: | OpenAIRE |
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