Cognitive remediation therapy does not enhance treatment effect in obsessive-compulsive disorder and anorexia nervosa: a randomized controlled trial
| Autor: | van Passel, B., Danner, U.N., Dingemans, A.E., Aarts, E., Sternheim, L.C., Becker, E.S., van Elburg, A.A., van Furth, E.F., Hendriks, G.-J., Cath, D.C., Trauma and Grief, Leerstoel Boelen, Methodology and statistics for the behavioural and social sciences, Leerstoel Klugkist, Leerstoel Engelhard, Experimental psychopathology, Leerstoel Hout |
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| Přispěvatelé: | Trauma and Grief, Leerstoel Boelen, Methodology and statistics for the behavioural and social sciences, Leerstoel Klugkist, Leerstoel Engelhard, Experimental psychopathology, Leerstoel Hout |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
FLEXIBILITY Stress-related disorders Donders Center for Medical Neuroscience [Radboudumc 13] Anorexia nervosa law.invention Experimental Psychopathology and Treatment 0302 clinical medicine Randomized controlled trial law QUALITY-OF-LIFE Obsessive-compulsive disorder 030212 general & internal medicine Applied Psychology SCALE Netherlands PLACEBO Cognitive flexibility General Medicine Middle Aged PREVALENCE Psychiatry and Mental health Clinical Psychology Eating disorders Treatment Outcome Cognitive remediation therapy Female Adult medicine.medical_specialty ANXIETY DISORDERS MOTOR INHIBITION Placebo VALIDATION 03 medical and health sciences Young Adult All institutes and research themes of the Radboud University Medical Center mental disorders medicine Humans business.industry EATING-DISORDERS medicine.disease Comorbidity Cognitive Remediation 030227 psychiatry Clinical trial Physical therapy Quality of Life business COMORBIDITY |
| Zdroj: | Psychotherapy and Psychosomatics, 89(4), 228-241. KARGER Psychotherapy and Psychosomatics, 89(4), 228. S. Karger AG Psychotherapy and Psychosomatics, 89, 4, pp. 228-241 Psychotherapy and psychosomatics, 89(4), 228-241. KARGER Psychotherapy and Psychosomatics, 89, 228-241 |
| ISSN: | 0033-3190 |
| Popis: | Background: Guideline-recommended therapies are moderately successful in the treatment of obsessive-compulsive disorder (OCD) and anorexia nervosa (AN), leaving room for improvement. Cognitive inflexibility, a common trait in both disorders, is likely to prevent patients from engaging in treatment and from fully benefiting from existing therapies. Cognitive remediation therapy (CRT) is a practical augmentation intervention aimed at ameliorating this impairing cognitive style prior to disorder-specific therapy. Objective: To compare the effectiveness of CRT and a control treatment that was not aimed at enhancing flexibility, named specialized attention therapy (SAT), as add-ons to treatment as usual (TAU). Methods: In a randomized controlled multicenter clinical trial, 71 adult patients with OCD and 61 with AN were randomized to ten twice-weekly sessions with either CRT or SAT, followed by TAU. Patients were evaluated at baseline, post-CRT/SAT, and after 6 and 12 months, with outcomes being quantified using the Yale-Brown Obsessive Compulsive Scale for OCD and the Eating Disorder Examination Questionnaire for AN. Results: Across study groups, most importantly CRT+TAU was not superior to control treatment (SAT)+TAU in reducing OCD and AN pathology. Contrary to expectations, SAT+TAU may have been more effective than CRT+TAU in patients being treated for OCD. Conclusions: CRT did not enhance the effect of TAU for OCD and AN more than SAT. Unexpectedly, SAT, the control condition, may have had an augmentation effect on TAU in OCD patients. Although this latter finding may have been due to chance, the effect of SAT delivered as a pretreatment add-on intervention for adults with OCD and AN merits future efforts at replication. |
| Databáze: | OpenAIRE |
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