Echinococcus multilocularis protoscoleces and hepatic cell activity in vitro
| Autor: | S. Al Nahhas, S. Walbaum, Anne-Françoise Pétavy, Marc Mesnil, C. Gabrion |
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| Rok vydání: | 1995 |
| Předmět: |
Male
Kupffer Cells Biology In Vitro Techniques Echinococcus multilocularis Cell Line Host-Parasite Interactions Mice Echinococcosis Albumins medicine Animals Secretion chemistry.chemical_classification Inflammation Albumin Transferrin 3T3 Cells biology.organism_classification Blood proteins Molecular biology In vitro Echinococcus Rats Infectious Diseases medicine.anatomical_structure chemistry Liver Hepatocyte Immunology Hepatic stellate cell Parasitology |
| Zdroj: | International journal for parasitology. 25(1) |
| ISSN: | 0020-7519 |
| Popis: | E. multilocularis protoscoleces were co-cultured with hepatic cells in the presence of IAR 20 or BALB c 3T3 cells. Hepatocyte activity was determined by assaying transferrin and albumin secretion in culture media. The level of these 2 plasma proteins is higher in hepatic/BALB/c 3T3 co-culture medium. In the presence of parasites, the transferrin level is unchanged while the production of albumin is stimulated during the first 48 h. Our results suggest that the albumin production could be attributed to a complex cellular cooperation between hepatocytes and activated Kupffer cells as previously observed in the acute inflammatory reaction. |
| Databáze: | OpenAIRE |
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