Ventricular arrhythmias in aortic valve disease: a further marker of impaired left ventricular function
| Autor: | H García del Castillo, Pilar Tornos, Manuel Alijarde, Victor Moreno, C. Martínez-Useros, J. Montoyo, Jordi Soler-Soler, G. Permanyer Miralda |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Aortic valve Cardiac Catheterization Cardiac Complexes Premature medicine.medical_specialty Heart Ventricles Aortic Valve Insufficiency Hemodynamics Cardiomegaly Regurgitation (circulation) Left ventricular hypertrophy Ventricular Function Left Muscle hypertrophy Electrocardiography Internal medicine medicine Humans Prospective Studies cardiovascular diseases Aged medicine.diagnostic_test business.industry Incidence Stroke Volume Aortic Valve Stenosis Middle Aged Prognosis medicine.disease Stenosis medicine.anatomical_structure Echocardiography Anesthesia Electrocardiography Ambulatory cardiovascular system Ventricular pressure Cardiology Female Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | International Journal of Cardiology. 34:49-56 |
| ISSN: | 0167-5273 |
| Popis: | One hundred and twenty stable patients with pure and severe aortic valve disease and without coronary lesions (aortic stenosis, 43 patients; aortic regurgitation, 45 patients; combined aortic stenosis and regurgitation, 32 patients) who had been submitted to haemodynamic studies were prospectively studied with standard electrocardiograms, M-mode echocardiograms, and 24-hour ambulatory electrocardiography (Holter recording). The frequency and complexity of ventricular arrhythmias were related to clinical parameters such as functional class, type of lesion and presence of syncope, and to parameters of left ventricular hypertrophy and function. Ventricular arrhythmias were present in 92% of patients. A high number of ventricular premature beats was directly correlated with parameters of complexity of the arrhythmia. A significant relation was found between electrocardiographic left ventricular hypertrophy and Ryan class (P less than 0.05), and an inverse relation between maximal number of ventricular premature beats in any hour and left ventricular ejection fraction (P less than 0.05). The group of patients with aortic regurgitation showed a higher total number of ventricular premature beats per 24 hours (P less than 0.001), a higher maximal number of these in any hour (P less than 0.01), a higher number of patients with pairs (P less than 0.001), and a higher number of patients in Ryan classes 3, 4A, 4B (P less than 0.01). This study shows a high incidence of ventricular arrhythmias in aortic valve disease, and especially in aortic regurgitation, with a significant relation between left ventricular hypertrophy and function, and number and complexity of arrhythmias. |
| Databáze: | OpenAIRE |
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