Herd protection against influenza

Autor: W. Paul Glezen
Rok vydání: 2006
Předmět:
Zdroj: Journal of Clinical Virology. 37:237-243
ISSN: 1386-6532
DOI: 10.1016/j.jcv.2006.08.020
Popis: Mortality and hospitalization rates due to influenza have risen despite increasing vaccine coverage for the most vulnerable population; however, those most vulnerable to complications and death are the least likely to respond to the vaccine. New strategies for influenza control are needed and indirect effectiveness (herd protection) has been demonstrated for several currently used vaccines - rubella, H. influenzae type b, pneumococcus varicella and hepatitis A. The Japanese schoolchildren program provided proof of concept of indirect effectiveness of influenza vaccine. The Central Texas field trial has demonstrated significant herd protection of adults utilizing the live, attenuated influenza vaccine (LAIV) to children. Immunization of
Databáze: OpenAIRE