Successful Pregnancy in a Hemodialysis Patient and Marked Resolution of Her Nephrogenic Systemic Fibrosis
| Autor: | John F. Greene, Mohanram Narayanan, Charles J. Foulks, Whitney A. High, Anand Khurana, Allan E. Nickel |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Urology Pregnancy Renal Dialysis medicine Humans Dialysis Skin medicine.diagnostic_test business.industry Gadodiamide Remission Induction Magnetic resonance imaging medicine.disease Fibrosis Transplantation Nephrology Nephrogenic systemic fibrosis Skin biopsy Female Kidney Diseases Radiology Hemodialysis business medicine.drug |
| Zdroj: | American Journal of Kidney Diseases. 51:e29-e32 |
| ISSN: | 0272-6386 |
| DOI: | 10.1053/j.ajkd.2007.12.037 |
| Popis: | Nephrogenic systemic fibrosis (NSF) is a recently recognized clinicopathologic entity. It is believed to be related to exposure to gadolinium-containing magnetic resonance imaging agents with gadolinium deposition in the tissues, including skin and other organs. It mainly affects patients on dialysis therapy. Pregnancy in dialysis patients is a rare occurrence. We present a case of a dialysis patient who developed NSF after exposure to gadodiamide and went on to have a successful pregnancy while on hemodialysis therapy. The patient had marked clinical and histological improvement in NSF during and after her pregnancy. This also correlated with decreasing gadolinium levels in skin biopsy tissue specimens. We discuss the interplay of factors involved in the successful pregnancy and improvement in NSF lesions in this patient. |
| Databáze: | OpenAIRE |
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