First detection of tetrodotoxin and high levels of paralytic shellfish poisoning toxins in shellfish from Sicily (Italy) by three different analytical methods
| Autor: | Mariagrazia Giacobbe, Samuela Capellacci, Andrew D. Turner, Antonella Penna, Giuseppe Polito, Karl J Dean, Silvia Casabianca, Luciana Tartaglione, Carmela Dell'Aversano |
|---|---|
| Přispěvatelé: | Dell'Aversano, Carmela, Tartaglione, Luciana, Polito, Giuseppe, Dean, Karl, Giacobbe, Mariagrazia, Casabianca, Silvia, Capellacci, Samuela, Penna, Antonella, Turner, Andrew D. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Environmental Engineering
Paralytic shellfish toxins Health Toxicology and Mutagenesis 0208 environmental biotechnology UHPLC-HILIC-MS/MS 02 engineering and technology Tetrodotoxin 010501 environmental sciences Biology 01 natural sciences chemistry.chemical_compound Mediterranean sea Tandem Mass Spectrometry medicine HPLC-FLD Animals Humans Shellfish Poisoning Environmental Chemistry Alexandrium spp Food science Paralytic shellfish poisoning Sicily Chromatography High Pressure Liquid Shellfish 0105 earth and related environmental sciences Saxitoxin fungi Chemistry (all) Fishes Public Health Environmental and Occupational Health food and beverages General Medicine General Chemistry medicine.disease Paralytic shellfish toxin Pollution HPLC-HILIC-HRMS/MS 020801 environmental engineering Shellfish poisoning Italy chemistry Alexandrium spp Paralytic shellfish toxins Tetrodotoxin UHPLC-HILIC-MS/MS HPLC-HILIC-HRMS/MS HPLC-FLD Seawater Bay |
| Zdroj: | Chemosphere 215 (2019): 881–892. doi:10.1016/j.chemosphere.2018.10.081 info:cnr-pdr/source/autori:Dell'Aversano, Carmela; Tattaglione, Luciana; Polito, Giuseppe; Dean, Karl; Giacobbe, Mariagrazia; Casabianca, Silvia; Capellacci, Samuela; Penna, Antonella; Turner, Andrew D./titolo:First detection of tetrodotoxin and high levels of paralytic shellfish poisoning toxins in shellfish from Sicily (Italy) by three different analytical methods/doi:10.1016%2Fj.chemosphere.2018.10.081/rivista:Chemosphere/anno:2019/pagina_da:881/pagina_a:892/intervallo_pagine:881–892/volume:215 |
| DOI: | 10.1016/j.chemosphere.2018.10.081 |
| Popis: | Paralytic shellfish toxins (PST) and tetrodotoxin (TTX) are naturally-occurring toxins that may contaminate the food chain, inducing similar neurological symptoms in humans. They are co-extracted under the same conditions and thus their combined detection is desirable. Whilst PST are regulated and officially monitored in Europe, more data on TTX occurrence in bivalves and gastropods are needed before meaningful regulations can be established. In this study, we used three separate analytical methods - pre-column oxidation with liquid chromatography and fluorescence detection, ultrahigh performance hydrophilic interaction liquid chromatography (HILIC) tandem mass spectrometry (MS/MS) and HILIC high resolution (HR) MS/MS - to investigate the presence of PST and TTX in seawater and shellfish (mussels, clams) collected in spring summer 2015 to 2017 in the Mediterranean Sea. Samples were collected at 10 sites in the Syracuse Bay (Sicily, Italy) in concomitance with a mixed bloom of Alexandrium minutum and A. pacificum. A very high PST contamination in mussels emerged, unprecedentedly found in Italy, with maximum total concentration of 10851 mu g saxitoxin equivalents per kg of shellfish tissue measured in 2016. In addition, for the first time TTX was detected in Italy in most of the analysed samples in the range 0.8-6.4 mu g TTX eq/kg. The recurring blooms of PST-producing species over the 3-year period, the high PST levels and the first finding of TTX in mussels from the Syracuse bay, suggest that monitoring programmes of PST and TTX in seafood should be activated in this geographical area. (C) 2018 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|