Chronic axonal sensory and autonomic polyneuropathy without motor involvement: a new ?chronic inflammatory neuropathy??
| Autor: | A. Zincone, Lodovico Frattola, Patrizia Santoro, Giovanni Tredici, Elio Agostoni, Chiara Gori, Guido Cavaletti |
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| Přispěvatelé: | Cavaletti, G, Santoro, P, Agostoni, E, Zincone, A, Gori, C, Frattola, L, Tredici, G |
| Rok vydání: | 1999 |
| Předmět: |
Pathology
medicine.medical_specialty Biopsy Sensation Disorder Inflammation Sensory system Axon Polyneuropathies Cerebrospinal fluid Prednisone Humans Medicine Peripheral Nerves medicine.diagnostic_test business.industry Middle Aged Autonomic Nervous System Disease medicine.disease Axons Autonomic nervous system Autonomic Nervous System Diseases Polyneuropathie Neurology Peripheral Nerve Anesthesia Sensation Disorders Chronic Disease Female Neurology (clinical) medicine.symptom business Inflammatory neuropathy Polyneuropathy Human medicine.drug |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1468-1331 1351-5101 |
| Popis: | We report the case of a woman with axonal sensory and autonomic neuropathy lasting several months who improved in association with steroid administration. During the course of her disease and in the follow-up, the patient underwent repeated cerebrospinal fluid (CSF) examinations, neurophysiological somatic, autonomic nervous system studies and sural nerve biopsy. Clinical and laboratory assessments demonstrated the occurrence of a monophasic, chronic sensory and autonomic neuropathy. A sural nerve biopsy suggested an axonopathy. After a progressive worsening of symptoms lasting about 6 months, steroid treatment was started and within 6 months a complete recovery, with normalization of the CSF findings, was observed. Although the 'chronic inflammatory neuropathies' are still debated entities, the features of this chronic, exclusively sensory and autonomic neuropathy are new, and the occurrence of a high protein level in the CSF, together with the favorable outcome associated with steroid treatment, suggests that our case might be another variant in this debated area. |
| Databáze: | OpenAIRE |
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