Kidney transplantation from SARS-CoV-2–positive deceased donor
| Autor: | Carlos A. Gomez, Jeffrey Campsen, Divya Raghavan, George Rofaiel, Miklos Z Molnar, Nicholas Baker, Isaac E. Hall, Hannah Imlay, Fuad S. Shihab, Robin D. Kim, Kimberly E. Hanson |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Brain Death
medicine.medical_specialty Tissue and Organ Procurement Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Clinical history Internal medicine Humans Immunology and Allergy Medicine Pharmacology (medical) Donor pool Kidney transplantation Transplantation Kidney Deceased donor medicine.diagnostic_test SARS-CoV-2 business.industry COVID-19 Nucleic acid test medicine.disease Kidney Transplantation Tissue Donors Organ procurement medicine.anatomical_structure business |
| Zdroj: | American Journal of Transplantation. 22:1280-1282 |
| ISSN: | 1600-6135 |
| DOI: | 10.1111/ajt.16905 |
| Popis: | To expand the available donor pool, many organ procurement organizations and transplant programs have begun to consider severe acute respiratory syndrome coronavirus(SARS-CoV-2) nucleic acid test positive candidates(1). It is becoming increasingly clear that not all donors with a positive nucleic acid amplification test for SARS-CoV-2 are contagious, and some of these organs can be transplanted with careful selection(2, 3). Data from 31 kidney transplants from living donors with resolved COVID-19 in India showed the safety of this approach(4). However, it is unknown whether kidneys from donors with active COVID-19 can also be safely transplanted(3, 5). Beyond the "active" infection designation, it is clinically possible to risk stratify donors with COVID-19 based on additional parameters such as clinical history and radiologic or laboratory findings. Here we present a case and 210-day outcome of a successful kidney transplantation from otherwise medically suitable SARS-CoV-2 PCR positive deceased donors. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text