Antibiotic prophylaxis in intraoral orthognathic surgery
| Autor: | John R. Hann, James E. Ruggles |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Adolescent medicine.drug_class Premedication Population Antibiotics Mandible Placebo Injections Intramuscular Random Allocation Double-Blind Method medicine Maxilla Humans Surgical Wound Infection Prospective Studies Antibiotic prophylaxis education education.field_of_study business.industry Penicillin G Surgery Osteotomy Penicillin Otorhinolaryngology Anesthesia Injections Intravenous Female Every Four Hours Oral Surgery Every Three Hours business medicine.drug |
| Zdroj: | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 42(12) |
| ISSN: | 0278-2391 |
| Popis: | A prospective randomized double-blind study was conducted to evaluate two prophylactic antibiotic regimens in a population of 40 patients undergoing intraoral orthognathic surgery. All patients received one intramuscular dose of 600,000 units procaine penicillin G and 400,000 units aqueous penicillin G preoperatively. Two million units aqueous penicillin G were administered intravenously every three hours intraoperatively and postoperatively three hours after the last intraoperative dose. One group of 20 patients then received 2 million units aqueous penicillin G intravenously every four hours for a total of 12 doses (two days) postoperatively. The second group of 20 patients received a placebo intravenously every four hours for a total of 12 doses (two days) postoperatively. Three infections occurred in the group of patients receiving the placebo postoperatively and none in the group of patients receiving the antibiotics postoperatively. |
| Databáze: | OpenAIRE |
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