Compensatory increase of functional connectivity density in adolescents with internet gaming disorder
Autor: | Yang Zhang, Xiaodong Li, Xin Qi, Quan Zhang, Xin Du, Peihong Gao, Guijin Du, Yongxin Yang |
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Rok vydání: | 2016 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Cognitive Neuroscience Rest Audiology computer.software_genre Immunoglobulin D Developmental psychology Correlation 03 medical and health sciences Behavioral Neuroscience Cellular and Molecular Neuroscience Young Adult 0302 clinical medicine Neuroimaging Voxel Neural Pathways medicine Humans Radiology Nuclear Medicine and imaging Attention Temporal cortex Brain Mapping Internet biology medicine.diagnostic_test Working memory Neuropsychology Brain Magnetic Resonance Imaging 030227 psychiatry Behavior Addictive Psychiatry and Mental health Memory Short-Term Neurology Video Games biology.protein Neurology (clinical) Psychology Functional magnetic resonance imaging computer 030217 neurology & neurosurgery |
Zdroj: | Brain imaging and behavior. 11(6) |
ISSN: | 1931-7565 |
Popis: | Behavioral studies have demonstrated visual attention bias and working memory deficits in individuals with internet gaming disorder (IGD). Neuroimaging studies demonstrated that individuals with IGD presented abnormalities in brain structures and functions including resting-state functional connectivity (rsFC) disturbance. However, most previous studies investigated IGD-related rsFC alterations by using hypothesis-driven methods with priori selection of a region of interest, which cannot provide a full picture of the rsFC changes in IGD individuals. In this study, we recruited 27 male IGD adolescents and 35 demographically matched healthy controls (HCs) to investigate abnormal connective property of each voxel within whole brain of IGD adolescents using resting-state functional connectivity density (rsFCD) method, and further to evaluate the relationship between altered rsFCD and behavioral performances of visual attention and working memory. The results exhibited no significant intergroup difference in behavioral performance (visual working memory and attention). The IGD adolescents exhibited higher global/long-range rsFCD in the bilateral dorsal lateral prefrontal cortex (DLPFC) and the right inferior temporal cortex (ITC)/fusiform compared with the HCs. Although no significant correlation survived after Bonferroni correction, higher global/long-range rsFCD of the bilateral DLPFC was correlated with the Young’s internet addiction test (IAT) score and/or behavioral performance in IGD adolescents using an uncorrected threshold of P |
Databáze: | OpenAIRE |
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