Frequency and prognostic factors of olfactory dysfunction after traumatic brain injury
| Autor: | Ståle Nordgård, Anne-Sofie Helvik, Toril Skandsen, Anne Vik, Kent Gøran Moen, Thomas Hummel, Mette Bratt |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Tomography Scanners X-Ray Computed Adolescent Traumatic brain injury Neuroscience (miscellaneous) Anosmia Computed tomography macromolecular substances Statistics Nonparametric 03 medical and health sciences Olfaction Disorders Young Adult 0302 clinical medicine Brain Injuries Traumatic Developmental and Educational Psychology medicine Humans 030223 otorhinolaryngology Aged Retrospective Studies medicine.diagnostic_test business.industry Middle Aged medicine.disease Prognosis Cross-Sectional Studies Logistic Models Anesthesia Quality of Life Female Neurology (clinical) medicine.symptom business Head 030217 neurology & neurosurgery Follow-Up Studies |
| Zdroj: | Brain injury. 32(8) |
| ISSN: | 1362-301X |
| Popis: | To assess the frequency and factors associated with posttraumatic olfactory dysfunction, including anosmia, in a follow-up of patients with moderate and severe traumatic brain injury (TBI).The setting was a cross-sectional study of patients that were consecutively included in the Trondheim TBI database, comprising injury-related variables. Eligible participants 18-65 years were contacted 9-104 months post trauma and asked olfactory-related questions. Those reporting possible posttraumatic change of olfaction were invited to further examination using the Sniffin' Sticks panel.Of 211 eligible participants, 182 (86.3%) took part in telephone interviews and 25(13.7%) were diagnosed with olfactory dysfunction. 60% of these, or 8.2% of all participants, had anosmia. In age-adjusted logistic regression analyses, fall (OR 2.5, 95% CI 1.0-6.2), skull base fracture (OR 2.9, 95% CI 1.2-7.1) and cortical contusion(s) (OR 6.0, 95% CI 2.1-17.3) were associated with olfactory dysfunction. In an analysis of anosmia, fall (OR 3.4, 95% CI 1.1-10.6) and cortical contusion(s) (OR 19.7, 95% CI 2.5-156.0) were associated with the outcome.Of the study participants 13.7% had olfactory dysfunction and 8.2% had anosmia. Higher age, trauma caused by fall and CT displaying skull base fracture and cortical contusion(s) were related to olfactory dysfunction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|