Acupuncture regulates the glucose metabolism in cerebral functional regions in chronic stage ischemic stroke patients--a PET-CT cerebral functional imaging study

Autor: Junjun Yang, Chunzhi Tang, Yangjia Lu, Shu-Xia Wang, Renyong Lin, Baoci Shan, Huiling Xiao, Shaoyang Cui, Yong Huang, Wei Shen, Xinsheng Lai, Shanshan Qu, Junqi Chen
Rok vydání: 2012
Předmět:
Male
medicine.medical_specialty
Acupuncture Therapy
Carbohydrate metabolism
lcsh:RC321-571
Cellular and Molecular Neuroscience
Fluorodeoxyglucose F18
Cerebral activating/deactivating effect
Waiguan (TE5)
Acupuncture
medicine
Humans
Single-Blind Method
lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry
Stroke
Cerebral Cortex
PET-CT
Dry needling
Brain Mapping
Ischemic stroke
business.industry
General Neuroscience
lcsh:QP351-495
PET-CT cerebral functional imaging
Middle Aged
medicine.disease
Needling/sham needling
Surgery
Functional imaging
Sham point
lcsh:Neurophysiology and neuropsychology
medicine.anatomical_structure
Glucose
Cerebral cortex
Anesthesia
Positron-Emission Tomography
Linear Models
Female
business
Tomography
X-Ray Computed
Acupuncture Points
Brodmann area
Research Article
Zdroj: BMC Neuroscience
BMC Neuroscience, Vol 13, Iss 1, p 75 (2012)
ISSN: 1471-2202
Popis: Background Acupuncture has been applied to aid in the recovery of post-stroke patients, but its mechanism is unclear. This study aims to analyze the relationship between acupuncture and glucose metabolism in cerebral functional regions in post-stroke patients using 18 FDG PET-CT techniques. Forty-three ischemic stroke patients were randomly divided into 5 groups: the Waiguan (TE5) needling group, the TE5 sham needling group, the sham point needling group, the sham point sham needling group and the non-needling group. Cerebral functional images of all patients were then acquired using PET-CT scans and processed by SPM2 software. Results Compared with the non-needling group, sham needling at TE5 and needling/sham needling at the sham point did not activate cerebral areas. However, needling at TE5 resulted in the activation of Brodmann Area (BA) 30. Needling/sham needling at TE5 and needling at the sham point did not deactivate any cerebral areas, whereas sham needling at the sham point led to deactivation in BA6. Compared with sham needling at TE5, needling at TE5 activated BA13, 19 and 47 and did not deactivate any areas. Compared with needling at the sham point, needling at TE5 had no associated activation but a deactivating effect on BA9. Conclusion Needling at TE5 had a regulating effect on cerebral functional areas shown by PET-CT, and this may relate to its impact on the recovery of post-stroke patients.
Databáze: OpenAIRE
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