Magnetic Field Alignment, a Perspective in the Engineering of Collagen-Silica Composite Biomaterials
| Autor: | Kenta Matsumoto, Noriyuki Hirota, Carole Aimé, Nicolas Debons, Toshiyuki Ikoma, Thibaud Coradin |
|---|---|
| Přispěvatelé: | Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP), Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Tokyo Institute of Technology [Tokyo] (TITECH) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
collagen
Scaffold Materials science [SDV]Life Sciences [q-bio] Composite number Nanotechnology 02 engineering and technology 010402 general chemistry Regenerative Medicine 01 natural sciences Biochemistry Regenerative medicine Microbiology Article Nanocomposites Silica nanoparticles Mice Cell Adhesion Animals Molecular Biology high magnetic field Tissue Scaffolds silica particles bionanocomposites 3T3 Cells 021001 nanoscience & nanotechnology Silicon Dioxide QR1-502 0104 chemical sciences 3. Good health Magnetic field Magnetic Fields Erratum 0210 nano-technology High magnetic field Tilapia biomaterials |
| Zdroj: | Biomolecules Biomolecules, Vol 11, Iss 749, p 749 (2021) Volume 11 Issue 5 Biomolecules, MDPI, 2021, 11 (5), pp.749. ⟨10.3390/biom11050749⟩ |
| ISSN: | 2218-273X |
| DOI: | 10.3390/biom11050749⟩ |
| Popis: | International audience; Major progress in the field of regenerative medicine is expected from the design of artificial scaffolds that mimic both the structural and functional properties of the ECM. The bionanocomposites approach is particularly well fitted to meet this challenge as it can combine ECM-based matrices and colloidal carriers of biological cues that regulate cell behavior. Here we have prepared bionanocomposites under high magnetic field from tilapia fish scale collagen and multifunctional silica nanoparticles (SiNPs). We show that scaffolding cues (collagen), multiple display of signaling peptides (SiNPs) and control over the global structuration (magnetic field) can be combined into a unique bionanocomposite for the engineering of biomaterials with improved cell performances. View Full-Text |
| Databáze: | OpenAIRE |
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