A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers
| Autor: | Lauro José Gregianin, Fabianne Carlesse, Henrique Manoel Lederman, Sandra Regina Loggetto, Arnaldo Lopes Colombo, Liane Esteves Daudt, Carmem Bonfim, Marjorie Vieira Batista, Maria Lucia de Martino Lee, Carla Renata Pacheco Donato Macedo, Eliana Benites, Analy Salles de Azevedo Melo, Álvaro Pimenta Dutra, Marcelo Luiz Abramczyk, Belinda Pinto Simões, Cláudio Galvão de Castro Junior, Adriana Seber, Vivian Siqueira Tostes |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Consensus medicine.medical_treatment lcsh:QR1-502 Criança Hematopoietic stem cell transplantation Opportunistic Infections lcsh:Microbiology Infecções fúngicas invasivas law.invention lcsh:Infectious and parasitic diseases 03 medical and health sciences Fungal infections Randomized controlled trial law Epidemiology medicine Pediatric oncology Humans lcsh:RC109-216 Intensive care medicine Child Children Cancer 0303 health sciences Hematologic cancer 030306 microbiology business.industry Hematopoietic Stem Cell Transplantation medicine.disease Neoplasias Transplantation Infectious Diseases Hematologic Neoplasms business Brazil Invasive Fungal Infections Medical literature |
| Zdroj: | Repositório Institucional da UFRGS Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS Brazilian Journal of Infectious Diseases v.23 n.6 2019 Brazilian Journal of Infectious Diseases Brazilian Society of Infectious Diseases (BSID) instacron:BSID Brazilian Journal of Infectious Diseases, Vol 23, Iss 6, Pp 395-409 (2019) Brazilian Journal of Infectious Diseases, Volume: 23, Issue: 6, Pages: 395-409, Published: 14 FEB 2020 |
| Popis: | In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early diagnosis and best clinical management of IFDs are also presented. This document summarizes practical recommendations that will certainly help pediatricians to best treat their patients suffering of invasive fungal diseases. Keywords: Fungal infections, Children, Cancer |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|