Waterborne Urinary Tract Infections: Have We Overlooked an Important Source of Exposure?

Autor: Heather K. Amato, Jay P. Graham, Renata Mendizábal-Cabrera, Danilo Alvarez, Brooke M. Ramay
Rok vydání: 2021
Předmět:
Zdroj: Am J Trop Med Hyg
ISSN: 1476-1645
0002-9637
Popis: The presence of intestinal pathogenic Escherichia coli in drinking water is well recognized as a risk for diarrhea. The role of drinking water in extraintestinal infections caused by E. coli—such as urinary tract infections (UTIs)—remains poorly understood. Urinary tract infections are a leading cause of outpatient infections globally, with a lifetime incidence of 50–60% in adult women. We reviewed the scientific literature on the occurrence of uropathogenic E. coli (UPEC) in water supplies to determine whether the waterborne route may be an important, overlooked, source of UPEC. A limited number of studies have assessed whether UPEC isolates are present in drinking water supplies, but no studies have measured whether their presence in water may increase UPEC colonization or the risk of UTIs in humans. Given the prevalence of drinking water supplies contaminated with E. coli across the globe, efforts should be made to characterize UTI-related risks associated with drinking water, as well as other pathways of exposure.
Databáze: OpenAIRE