A severe case of vasoplegic shock following metformin overdose successfully treated with methylene blue as a last line therapy
| Autor: | Michaela Cartner, Rachel Erin Graham, James Winearls |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Resuscitation Article chemistry.chemical_compound Refractory medicine Humans Vasoconstrictor Agents Gliclazide business.industry Metabolic acidosis Shock General Medicine medicine.disease Metformin Surgery Methylene Blue Distributive shock chemistry Shock (circulatory) Vasoplegia Fluid Therapy medicine.symptom Drug Overdose business Acidosis Methylene blue medicine.drug |
| Zdroj: | BMJ case reports. 2015 |
| ISSN: | 1757-790X |
| Popis: | A 44-year-old man presented to hospital 24 h after an intentional overdose of metformin and gliclazide. He had a critical metabolic acidosis on presentation with a pH of 6.88, and very rapidly deteriorated into distributive shock refractory to large volume fluid resuscitation and massive doses of vasopressors. We introduced a methylene blue infusion as a rescue therapy in an attempt to improve the patient's haemodynamics, which was successful. The patient made a full recovery with no long-term sequelae. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|