An automated microfluidic platform for the screening and characterization of novel hepatitis B virus capsid assembly modulators
| Autor: | Tamás Vermes, Mark Kielpinski, Thomas Henkel, Miquel A. Pericàs, Esther Alza, Angelica Corcuera, Helmut Buschmann, Thomas Goldner, Andreas Urban |
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| Jazyk: | angličtina |
| Předmět: |
0303 health sciences
Hepatitis B virus General Chemical Engineering Microfluidics General Engineering 010402 general chemistry 01 natural sciences Antiviral Agents 3. Good health 0104 chemical sciences Analytical Chemistry 03 medical and health sciences Capsid Organic Chemicals 030304 developmental biology |
| Zdroj: | Analytical Methods |
| ISSN: | 1759-9679 1759-9660 |
| DOI: | 10.1039/d1ay01227d |
| Popis: | A fully automated microfluidic system was developed to screen for novel anti-HBV capsid assembly modulators. High-resolution dose–response curves were generated using convection-dominated Taylor–Aris dispersion of the screening compounds. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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