A Validated HPLC Method for the Determination of Vanillyl Butyl Ether in Cosmetic Preparations
| Autor: | Joaquin Melendez, Antonio Alberola, Gema Muedra, Francisco Ríos, Francisco Trigo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Aging
vanillyl butyl ether Method validation Pharmaceutical Science Dermatology 030226 pharmacology & pharmacy High-performance liquid chromatography lcsh:Chemistry 030207 dermatology & venereal diseases 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Cosmetic product Chemical Engineering (miscellaneous) Acetonitrile Hplc method Reproducibility Vanillyl butyl ether Chromatography Isocratic elution Chemistry Extraction (chemistry) method validation cosmetic product Repeatability VANILLYL BUTYL ETHER lcsh:QD1-999 Surgery HPLC |
| Zdroj: | Digibug. Repositorio Institucional de la Universidad de Granada instname Cosmetics, Vol 4, Iss 1, p 9 (2017) |
| Popis: | A specific HPLC (High-Performance Liquid Chromatography) method has been developed and validated for the determination of vanillyl butyl ether in cosmetic products. The extraction procedure with an isopropanol water 1:1 mixture is described. The method uses a RP-C-18 column with isocratic elution and an ultraviolet (UV) detector. The mobile phase consists of a mixture of acetonitrile and buffer (Na2HPO4 20 mM in water) (30:70 v/v) with a variable flow rate. The method was validated with respect to accuracy, precision (repeatability and reproducibility), specificity and linearity. The procedure described here is simple, selective and reliable for routine quality control analysis and stability tests of commercially available cosmetic products. Francisco Ríos acknowledges the support fromthe Spanish Ministry of Economy, Industry and Competitiveness within the postdoctoral grant “Ayudas para contratos Torres Quevedo” (PTQ-15-07879). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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