Validation of the 2016 ASE/EACVI Guideline for Diastolic Dysfunction in Patients With Unexplained Dyspnea and a Preserved Left Ventricular Ejection Fraction

Autor: M. Louis Handoko, Albert C. van Rossum, Frances S. de Man, Anton Vonk Noordegraaf, Arno A van de Bovenkamp, Vidya Enait, Frank T P Oosterveer, Harm Jan Bogaard
Přispěvatelé: Cardiology, ACS - Heart failure & arrhythmias, Pulmonary medicine, ACS - Pulmonary hypertension & thrombosis, APH - Personalized Medicine
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 18 (2021)
van de Bovenkamp, A A, Enait, V, de Man, F S, Oosterveer, F T P, Bogaard, H J, Vonk Noordegraaf, A, van Rossum, A C & Handoko, M L 2021, ' Validation of the 2016 ase/eacvi guideline for diastolic dysfunction in patients with unexplained dyspnea and a preserved left ventricular ejection fraction ', Journal of the American Heart Association, vol. 10, no. 18, e021165, pp. e021165 . https://doi.org/10.1161/JAHA.121.021165, https://doi.org/10.1161/JAHA.121.021165
Journal of the American Heart Association, 10(18):e021165. Wiley-Blackwell
ISSN: 2047-9980
Popis: Background Echocardiography is considered the cornerstone of the diagnostic workup of heart failure with preserved ejection fraction. Thus far, validation of the 2016 American Society of Echocardiography/European Association of Cardiovascular Imaging (ASE/EACVI) echo‐algorithm for evaluation of diastolic (dys)function in a patient suspected of heart failure with preserved ejection fraction has been limited. Methods and Results The diagnostic performance of the 2016 ASE/EACVI algorithm was assessed in 204 patients evaluated for unexplained dyspnea or pulmonary hypertension with echocardiogram and right heart catheterization. Invasively measured pulmonary capillary wedge pressure (PCWP) was used as the gold standard. In addition, the diagnostic performance of H 2 FPEF score and NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) were evaluated. There was a poor correlation between indexed left atrial volume, E/e′ (septal and average) or early mitral inflow (E), and PCWP ( r =0.25–0.30, P values all r =0.17, P 2 FPEF score had a modest correlation with PCWP ( r =0.44, P r =0.24, P Conclusions The 2016 ASE/EACVI algorithm for the assessment of diastolic function has a limited diagnostic accuracy in patients evaluated for unexplained dyspnea and/or pulmonary hypertension, and especially sensitivity to detect diastolic dysfunction was low.
Databáze: OpenAIRE
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