Phototherapy-Induced Hypocalcemia in Newborn Rats: Prevention by Melatonin
| Autor: | William H Bergstrom, David O Hakanson |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Time Factors Hydrocortisone Light chemistry.chemical_element Exogenous melatonin Calcium Melatonin chemistry.chemical_compound Fluorescent light Corticosterone Internal medicine medicine Animals Humans Multidisciplinary Hypocalcemia business.industry Spectrum Analysis Infant Newborn Phototherapy Jaundice Neonatal Rats Disease Models Animal Endocrinology Increased calcium Animals Newborn chemistry Female Spectrum analysis business hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Science. 214:807-809 |
| ISSN: | 1095-9203 0036-8075 |
| Popis: | When young rats are exposed to white fluorescent light the concentration of calcium in their serum decreases. This effect is prevented by shielding the occiput, by inhibiting corticosterone synthesis, and by exogenous melatonin. Furthermore, the expected hypocalcemic response to cortisol injection is prevented by melatonin. Light-induced hypocalcemia may result from increased calcium uptake by bone when the blocking effect of melatonin decreases after pineal inhibition by transcranial illumination. |
| Databáze: | OpenAIRE |
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