Vesicles as Initial Skin Manifestation of Disseminated Fusariosis after Non-myeloablative Stem Cell Transplantation
| Autor: | Junichi Ueyama, Eiji Kusumi, Shigesaburo Miyakoshi, Akiko Kishi, Masahiro Kami, Tamae Hamaki, S. Taniguchi, Shinichi Morinaga, Kuniaki Ohara, Hiroshi Iwata, Yoshitomo Muto, Yukiko Kishi |
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| Rok vydání: | 2004 |
| Předmět: |
Male
Fusariosis Cancer Research Pathology medicine.medical_specialty Transplantation Conditioning Multiple Organ Failure Lymphoma Mantle-Cell Human leukocyte antigen Skin Diseases Blister Fatal Outcome Fusarium medicine Humans business.industry Vesicle Hematopoietic Stem Cell Transplantation Hematology Disseminated Fusariosis Middle Aged medicine.disease Transplantation Mycoses Oncology Sputum Mantle cell lymphoma Stem cell medicine.symptom business Fungemia |
| Zdroj: | Leukemia & Lymphoma. 45:631-633 |
| ISSN: | 1029-2403 1042-8194 |
| DOI: | 10.1080/1042819031000151941 |
| Popis: | A 52-year-old man underwent non-myeloablative stem cell transplantation from his HLA identical sister for the treatment of mantle cell lymphoma. On day 0, he developed a high-grade fever, watery diarrhea and vesicles scattered on the skin. Well experienced dermatologists diagnosed these lesions as VZV reactivation. High dose antiviral agents were ineffective, and Fusarium solani was cultured from his stool and sputum. Systemic fusariosis progressed rapidly and he died of multiorgan failure on day 18. It is sometimes difficult to differentiate between viral and fungal blisters based on macroscopic examinations. We recommend early histopathological examination of the skin, when HSCT recipients develop vesicles. |
| Databáze: | OpenAIRE |
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