Primary closure of choledochotomy using CO2 laser: Comparison with suture closure

Autor: Clyde C. Vanterpool, Steven Bolton, Morris E. Gales, Robert P. Hawkins
Rok vydání: 1993
Předmět:
Zdroj: Lasers in Surgery and Medicine. 13:429-433
ISSN: 1096-9101
0196-8092
Popis: This study was designed to compare laser welding to suture closure of the common bile duct (CBD). A 12 mm linear choledochotomy was closed in 12 mongrel dogs using tissue welding lowenergy CO2 laser. Tissue welding was accomplished at 5.0 w/cm2 for 120 sec. Twelve similar mongrel dogs (control) were treated with CBD closure using 5/0 Vicryl (polyglactin 910, Ethicon, Inc., Somerville, NJ) interrupted simple stitches. All animals were sacrificed at six weeks. Gross and histologic evaluation of the choledochotomy site were performed. There were no statistical differences in parameters of comparison in the two groups. These parameters were pre- and post-treatment measurements of liver function tests, stenosis, and dehiscence. However, it must be noted that there was a 33% (4/12) incidence of dehiscence and death in the CO2 laser welded choledochorrhaphy. This result, although not statistically significant, is clinically significant. We conclude that the tensile strength of CO2 laser welded CBDs must be optimized and that these results are preliminary and still unreliable to recommend for clinical adaptability. © 1993 Wiley-Liss, Inc.
Databáze: OpenAIRE