From molecular evolution to biobricks and synthetic modules: a lesson by the bacterial flagellum
| Autor: | J.S. Schuhmacher, Patrick Pausch, Florian Altegoer, Gert Bange |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Bacteria
Bioengineering Biology Flagellum Flagellar filament Bacterial Physiological Phenomena Models Biological Cell biology Macromolecular assembly Evolution Molecular Molecular evolution Flagella biology.protein Synthetic Biology Directed Molecular Evolution Carrier Proteins Molecular Biology Flagellin Biotechnology Ultrasonography |
| Zdroj: | Biotechnologygenetic engineering reviews. 30(1-2) |
| ISSN: | 0264-8725 |
| Popis: | The bacterial flagellum is a motility structure and represents one of the most sophisticated nanomachines in the biosphere. Here, we review the current knowledge on the flagellum, its architecture with respect to differences between Gram-negative and Gram-positive bacteria and other species-specific variations (e.g. the flagellar filament protein, Flagellin). We further focus on the mechanism by which the two nucleotide-binding proteins FlhF and FlhG ensure the correct reproduction of flagella place and number (the flagellation pattern). We will finish the review with an overview of current biotechnological applications, and a perspective of how understanding flagella can contribute to developing modules for synthetic approaches. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|