Development of the D. melanogaster caudal segments involves suppression of the ventral regions of A8, A9 and A10
| Autor: | Gregory S. Turenchalk, Thomas B. Kornberg, G. Packert, M. Sawyer, E. Gustavson, J. A. Mack, David T. Kuhn, Th E. Sprey |
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| Rok vydání: | 1992 |
| Předmět: |
Nervous system
animal structures Embryo Nonmammalian Sense organ Gene Expression Drosophilidae Abdomen medicine Melanogaster Morphogenesis Animals Tuft Microscopy Phase-Contrast Molecular Biology biology Genes Homeobox Sense Organs Anatomy biology.organism_classification engrailed medicine.anatomical_structure Drosophila melanogaster Mutation Microscopy Electron Scanning Homeotic gene Developmental Biology |
| Zdroj: | Development (Cambridge, England). 116(1) |
| ISSN: | 0950-1991 |
| Popis: | Whereas the segmental organization of the thorax and anterior abdomen is morphologically delineated in both the Drosophila larva and adult, segments in the head and caudal regions lack such well-defined boundaries. Consequently, the organization of these regions has been difficult to decipher. In this study, transformations caused by the bithorax-complex homeotic mutants 48, M3, Ultraabdominal-1 (Uab1) and tumorous-head-3 (tuh3), as well as the patterns of engrailed gene expression have been analyzed to investigate the segmental organization of the caudal segments. A special emphasis was placed on sense organs appearing in abdominal segments 8, 9 and 10 (A8–A10): We find that: (1) transformations in the caudal segments obey parasegmental borders; (2) the sense organs on A8, A9, and A10 are probably homologous to the pits and hairs in anterior A1–A7; (3) except for the larval anal tuft and the anterior side of A8, all structures in larval segments A8, A9 and A10 are dorsal/lateral in origin; and (4) dorsalization of embryonic A8 and A9 cells leaves space ventrally for A10, as it follows the contracting ventral nervous system during the embryological process of germ band contraction. |
| Databáze: | OpenAIRE |
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