Sex-related differences in catheter ablation of atrial fibrillation: a systematic review and meta-analysis
| Autor: | Xiaocheng Cheng, Lei Gao, Shu Qin, Dongying Zhang, Jian Liu, Qiongwen Hu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Catheter ablation Global Health Pericardial effusion Recurrence Risk Factors Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans Prospective cohort study Stroke Atrial tachycardia business.industry Surrogate endpoint Incidence Atrial fibrillation Odds ratio medicine.disease Prognosis Catheter Ablation medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21(10) |
| ISSN: | 1532-2092 |
| Popis: | Aims The sex-related differences in the clinical outcomes of rhythm and safety after catheter ablation remain unclear. The purpose of this study was to compare the clinical outcomes of catheter ablation for atrial fibrillation (AF) in women and men. Methods and results The Medline and EMBASE databases were searched for published articles up to December 2018. Studies that met our predefined inclusion criteria were included. The primary endpoints were freedom from AF/atrial tachycardia (AT) recurrence, stroke/transient ischaemic attack (TIA), and all-cause mortality. After literature search and detailed assessment, 19 observational studies (151 370 patients; 34% women) were identified. Our analyses showed that the rate of freedom from AF/AT recurrence was lower in women than men at the 2.4-year follow-up [odds ratio (OR): 0.75, 95% confidence interval (CI) 0.69–0.81; P Conclusions Women who underwent catheter ablation of AF might experience lower efficacy and a higher risk of stroke/TIA and major complications than men. The reasons for these sex-related differences need to be further studied. |
| Databáze: | OpenAIRE |
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