Fluorescent quantum dots: An insight on synthesis and potential biological application as drug carrier in cancer
| Autor: | Neha Singla, Akanksha Sharma, Indu Pal Kaur, Neeraj Choudhary, Udit Soni, Pavani Sriram, Ashish Suttee, P. Tandale, J. B. Singh, Gurpal Singh, Ananya Shukla, Ravi Pratap Barnwal |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Materials science QH301-705.5 Biophysics Quantum dot Nanotechnology QD415-436 Review Article Biochemistry Nanomaterials 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Nanomedicine Nanocrystal 030220 oncology & carcinogenesis Theranostic agent Drug delivery Nano Biology (General) Drug carrier Quantum |
| Zdroj: | Biochemistry and Biophysics Reports BASE-Bielefeld Academic Search Engine Biochemistry and Biophysics Reports, Vol 26, Iss, Pp 100962-(2021) |
| ISSN: | 2405-5808 |
| Popis: | Quantum dots (QDs) are nanocrystals of semiconducting material possessing quantum mechanical characteristics with capability to get conjugated with drug moieties. The particle size of QDs varies from 2 to 10 nm and can radiate a wide range of colours depending upon their size. Their wide and diverse usage of QDs across the world is due to their adaptable properties like large quantum yield, photostability, and adjustable emission spectrum. QDs are nanomaterials with inherent electrical characteristics that can be used as drug carrier vehicle and as a diagnostic in the field of nanomedicine. Scientists from various fields are aggressively working for the development of single platform that can sense, can produce a microscopic image and even be used to deliver a therapeutic agent. QDs are the fluorescent nano dots with which the possibilities of the drug delivery to a targeted site and its biomedical imaging can be explored. This review is mainly focused on the different process of synthesis of QDs, their application especially in the areas of malignancies and as a theranostic tool. The attempt is to consolidate the data available for the use of QDs in the biomedical applications. Highlights • QDs are nonmaterial's that can be used for drug delivery, imaging and diagnostic tool in the field of nanomedicine. • The various approaches to synthesize the QDs were explored. • QDs are accepted in the treatment strategies due to their biocompatibility with human physiology. • QDs posses' several biomedical application particularly in the area of cancer theranostics. • Fluorescents dots (QDs) can illuminate the complicated terrain of oncology sciences, novel biomarkers and a patient compliant treatment regimens. |
| Databáze: | OpenAIRE |
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