Risk and patterns of brain metastases in colorectal cancer
| Autor: | Wei Shone Chen, Jen Kou Lin, Jeng Kae Chiang, Fang Chu Ko, Tzu Chen Lin, Jacqueline M. Liu |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Oncology medicine.medical_specialty Lung Neoplasms Colorectal cancer medicine.medical_treatment Metastasis Risk Factors Surgical oncology Internal medicine medicine Humans Survival rate Aged Retrospective Studies Aged 80 and over Univariate analysis Brain Neoplasms business.industry Incidence Gastroenterology General Medicine Middle Aged medicine.disease Combined Modality Therapy Colorectal surgery Survival Rate Radiation therapy Treatment Outcome Female Colorectal Neoplasms business Brain metastasis |
| Zdroj: | Diseases of the Colon & Rectum. 42:1467-1471 |
| ISSN: | 0012-3706 |
| Popis: | PURPOSE: In patients with colorectal cancer, brain metastasis is infrequent. This study aims to elucidate the risk, pattern of occurrence, and survival time after different treatment modalities. METHODS: A retrospective review of all patients with colorectal cancer admitted to the Veterans General Hospital-Taipei between 1970 and 1996 from our hospital was performed. Univariate analysis for survival determination was performed. RESULTS: Brain metastases developed subsequent to surgery for colorectal cancer in 53 well-documented patients, at a median of 36 months after surgery. Brain metastases were more commonly seen in rectal cancer and often occurred concurrently with lung metastases. Forty of these patients received active intervention in terms of surgery, chemotherapy, or radiotherapy, with surgical intervention achieving a significantly increased mean survival time (± standard deviation) compared with chemotherapy or radiotherapy or both of 86.6±17.35vs. 2.9±0.59 months (P |
| Databáze: | OpenAIRE |
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