The prognostic value of long noncoding RNA activated by TGF-β in digestive system cancers
| Autor: | Houyu Duan, Xiang Ding, Hesheng Luo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Oncology medicine.medical_specialty Digestive System Neoplasms 03 medical and health sciences 0302 clinical medicine digestive system Transforming Growth Factor beta Pancreatic cancer Internal medicine Biomarkers Tumor cancer Humans Medicine lncRNA-ATB 030212 general & internal medicine Survival rate Aged business.industry Hazard ratio Case-control study Cancer General Medicine Middle Aged Prognosis medicine.disease Confidence interval meta-analysis Survival Rate Case-Control Studies Lymphatic Metastasis 030220 oncology & carcinogenesis Relative risk Meta-analysis Female RNA Long Noncoding business Systematic Review and Meta-Analysis Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| DOI: | 10.1097/md.0000000000021324 |
| Popis: | Background: To systematically evaluate whether the expression level of long non-coding RNA activated by transforming growth factor-β (lncRNA-ATB) is correlated with the prognosis of digestive system cancer (DSC) patients. Methods: PubMed, Embase, Cochrane Library, Web of Science, Springerlink, Nature, and Karger databases were searched up to April 20, 2019 by 2 experienced researchers independently. The quality of studies was assessed with the Newcastle-Ottawa scale. The Review Manager 5.2 and STATA 12.0 software were used for this meta-analysis. Result: Eleven studies with 1227 DSC patients were included in the meta-analysis. Except for pancreatic cancer, high expression of lncRNA-ATB was associated with lymph node metastasis (risk ratio (RR) = 1.26, 95% confidence interval (CI): 1.12–1.42, P |
| Databáze: | OpenAIRE |
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