Prevalence and distribution of single and multiple HPV infections in cytologically abnormal cervical samples from Italian women
| Autor: | Giuseppe Ciravolo, Federica Salinaro, M. A. De Francesco, Nino Manca, B. Valloncini, Claudio Schreiber, Franco Gargiulo |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Hpv genotypes
Oncology Adult Cancer Research medicine.medical_specialty Hpv genotyping Uterine Cervical Neoplasms Biology Roche Linear Array Virology Internal medicine Genotype medicine Prevalence Humans Papillomaviridae Aged Cervical cancer Vaginal Smears Hpv types Papillomavirus Infections HPV infection virus diseases Middle Aged medicine.disease Uterine Cervical Dysplasia female genital diseases and pregnancy complications Infectious Diseases Italy Cohort DNA Viral Female |
| Popis: | The prevalence of single and multiple HPV infections was assessed over a cohort of 213 women with cytological abnormalities and its association with cervical neoplasia established. Roche linear array HPV genotyping test was used to identify HPV genotypes. The most prevalent HPV genotypes in cervical cancer samples were HPV16 (61.2%), HPV52 (16.1%), HPV18 (12.9%) and HPV 31 (9.6%). Multiple HR and LR HPV infections, comprising between two and 5+ HPV types, were identified in 49.7% of samples, with a significantly lower number in severe dysplasia and cervical cancer samples (p |
| Databáze: | OpenAIRE |
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