Radiocalcium absorption is reduced in postmenopausal women with vertebral and most types of peripheral fractures
Autor: | Peter D. O’Loughlin, B. E. Christopher Nordin, Howard A. Morris, Michael Horowitz, Allan G. Need |
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Přispěvatelé: | Morris, Howard, Nordin, B.E.Christopher, O'Loughlin, Peter, Need, Allan G, Horowitz, M |
Rok vydání: | 2003 |
Předmět: |
musculoskeletal diseases
Humeral Fractures medicine.medical_specialty Endocrinology Diabetes and Metabolism Radiography Osteoporosis Wrist Absorption Bone remodeling Fractures Bone radiocalcium Risk Factors medicine Humans Humerus Tibia peripheral Osteoporosis Postmenopausal Aged postmenopausal Hip Fractures business.industry Calcium Radioisotopes Middle Aged Wrist Injuries medicine.disease Surgery medicine.anatomical_structure Orthopedic surgery Spinal Fractures Female Ankle business Leg Injuries |
Zdroj: | Osteoporosis International. 15:27-31 |
ISSN: | 1433-2965 0937-941X |
DOI: | 10.1007/s00198-003-1493-1 |
Popis: | Intestinal calcium absorption accounts for 60% of the variance in calcium balance and is therefore a potentially very important determinant of bone status. Whether measured by the balance technique or with radiocalcium, it is known to be significantly reduced in postmenopausal women with vertebral and hip fractures. By contrast, there is very little information about calcium absorption in other types of postmenopausal fracture. We now report a series of 549 untreated, Caucasian postmenopausal women in whom we recorded prevalent fractures, measured radiocalcium absorption, and obtained radiographs of the lateral thoracic and lumbar spine. Of these women, 172 had no prevalent fractures, showed normal spine radiographs, and served as controls; 72 had one or more peripheral fractures but normal spine radiographs; 147 had one or more wedged or crushed vertebrae but no peripheral fractures; and 158 had a history of peripheral fracture and one or more fractured vertebrae. Age-adjusted radiocalcium absorption was significantly lower in the two groups with spinal fractures than in the controls ( P |
Databáze: | OpenAIRE |
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