Аn affordability of statins therapy - comparative analysis between Ukraine and Bulgaria
| Autor: | Manoela Manova, Alexandra Savova, Zornitsa Mitkova, L. Iakovlieva, Guenka Petrova, O. Tkachova |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Working hours
Atorvastatin 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Environmental health Average price Medicine Drugs Generic Humans Rosuvastatin 030212 general & internal medicine Prices per DDD Bulgaria health care economics and organizations Consumption (economics) Affordability business.industry Health Policy lcsh:Public aspects of medicine Commerce Statins nutritional and metabolic diseases lcsh:RA1-1270 medicine.disease Price ratio Costs and Cost Analysis Statin therapy Hydroxymethylglutaryl-CoA Reductase Inhibitors business Ukraine Dyslipidemia medicine.drug Research Article |
| Zdroj: | BMC Health Services Research, Vol 19, Iss 1, Pp 1-8 (2019) BMC Health Services Research |
| ISSN: | 1472-6963 |
| DOI: | 10.1186/s12913-019-4736-3 |
| Popis: | Background The statins are а developing group of cardiovascular medicines, widely used for dyslipidemia. As a whole statins consumption leads to reduction in cardiovascular events and death, and improves the disease control. The main study issue considers the differences in an affordability to lipid lowering medicines in the countries with the highest morbidity and mortally rate within and outside EU. The affordability has been researched by exploring the price differences and average wages. Methods On total 7 international nonproprietary names and 19 dosage forms available on both markets are observed during 2013–2016. An average, minimum, and maximum retail prices per DDD, standard deviation (SD) has been calculated for all marketed dosage forms. A price ratio between the minimal and maximal price per DDD is estimated in order to evaluate their difference. Affordability of the treatment is determined as the number of working hours per month needed for patient to purchase medicines for a monthly therapy. Results Large variations of price per DDD, SD and the average price exist between different dosage forms in both countries. The highest value of a price ratio is observed for 5 mg rosuvastatin in Bulgaria and 10 mg rosuvastatin in Ukraine. The number of working hours needed to cover monthly therapy has increased during 2013–2016 in Ukraine. The most affordable is treatment with a generic atorvastatin in Bulgaria and generic rosuvastatin in Ukraine. The most expensive rosuvastatin in Bulgaria and atorvastatin in Ukraine are found as the least affordable for a monthly therapy. Conclusions The decrease of prices for statins is not the only reason influencing patients’ affordability to therapy for statin therapy in Ukraine and Bulgaria. The difference in affordability in Ukraine and Bulgaria is affected mainly by the economic development in the country as well as wages variation. |
| Databáze: | OpenAIRE |
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