| Popis: |
Previous evidence suggested that high fat dairy products consumption during pregnancy and lactation were associated with lower composition of linoleic acid in breast milk (Jonsson et al. 2016; Park et al. 1999). From our previous evidence, high linoleic acid in breast milk, leading to an unbalanced ratio of PUFA n-6 to PUFA n-3, was associated with a poorer cognitive development in children (Bernard et al. 2015; Bernard et al. 2017). Tissue composition of certain odd chain fatty acids (OCS-Fas), heptadecanoic (C17:0) and pentadecanoic (C15:0) acids are related to dairy fat intake. Using these biomarkers, potential benefit of maternal dairy fat intake on children cognitive development can be studied. Besides of their potential indirect effect, C17:0 and C15:0 were associated with lower risk of sclerosis, coronary heart disease, type II diabetes mellitus and cancer (Jenkins, West, and Koulman 2015). It was hypothesized that OCS-FAs increase membrane fluidity. By their ability to pass through the placental barrier and into breastmilk (Gozzo et al. 1982), it has been suggested that OCS-FAs could cross the cerebral endothelium as well and influence early postnatal brain development (Jenkins, West, and Koulman 2015). |
