Analytical applications of oscillatory chemical reactions: Determination of some pharmaceutically and biologically important compounds
| Autor: | D Natasa Pejic, Z Ljiljana Kolar-Anic, R Slobodan Anic |
|---|---|
| Jazyk: | srbština |
| Rok vydání: | 2012 |
| Předmět: |
Detection limit
Analyte oscillatory reaction Chromatography 010405 organic chemistry Chemistry Calibration curve General Chemical Engineering Kinetics Continuous stirred-tank reactor General Chemistry pharmaceutical preparations lcsh:Chemical technology 010402 general chemistry 01 natural sciences Chemical reaction 0104 chemical sciences Matrix (chemical analysis) flow reactor analyte pulse perturbation technique lcsh:TP1-1185 Routine analysis |
| Zdroj: | Hemijska industrija (2012) 66(2):153-164 Hemijska Industrija, Vol 66, Iss 2, Pp 153-164 (2012) |
| ISSN: | 0367-598X |
| Popis: | Novel analytical methods for quantitive determination of analytes based on perturbations of oscillatory chemical reactions realized under open reactor conditions (continuosly fed well stirred tank reactor, CSTR), have been developed in the past twenty years. The proposed kinetic methods are generally based on the ability of the analyzed substances to change the kinetics of the chemical reactions matrix. The unambiguous correlation of quantitative characteristics of perturbations, and the amount (concentration) of analyte expressed as a regression equation, or its graphics (calibration curve), enable the determination of the unknown analyte concentration. Attention is given to the development of these methods because of their simple experimental procedures, broad range of linear regression ( 10-7 10-4 mol L-1) and low limits of detection of analytes ( 10-6 10-8 mol L1, in some cases even lower than 10-12 mol L-1). Therefore, their application is very convenient for routine analysis of various inorganic and organic compounds as well as gases. This review summarizes progress made in the past 5 years on quantitative determination of pharmaceutically and biologically important compounds. |
| Databáze: | OpenAIRE |
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