Combined mutagenic action of chemicals and radiation in diploid yeast
| Autor: | K.B. Anjaria, U. Madhvanath |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Genetics
Mutation biology Statistics as Topic fungi Saccharomyces cerevisiae Gene Conversion General Medicine Yeast strain Methyl Methanesulfonate biology.organism_classification medicine.disease_cause 4-Nitroquinoline-1-oxide Yeast Ionizing radiation Combined treatment Biochemistry Gamma Rays Mitotic gene conversion Ethyl Methanesulfonate Radiation Ionizing medicine Ploidy |
| Zdroj: | Mutation Research Letters. 120:111-119 |
| ISSN: | 0165-7992 |
| Popis: | The interaction between the mutagenic action of chemicals and radiation was studied by using a diploid yeast strain Saccharomyces cerevisiae BZ 34 with mitotic gene conversion as the end-point. The cells were treated with EMS, MMS or 4-NQO alone or in combination with gamma-radiation. The 2 alkylating agents EMS and MMS produced an additive mutagenic response, whereas 4-NQO exhibited an antagonistic effect in the combined treatment with gamma-radiation. |
| Databáze: | OpenAIRE |
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