Encephalomyeloneuropathy with ganglionitis of the myenteric plexuses in the absence of cancer
| Autor: | Dikran S. Horoupian, Yehum Kim |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Pathology
medicine.medical_specialty Neuronophagia Ileus Myenteric Plexus Neuritis Phagocytosis Ganglia Spinal Humans Medicine Encephalomyelitis Ganglia Autonomic Myenteric plexus Barium enema Neurons business.industry Middle Aged medicine.disease Spinal cord digestive system diseases Pons Ganglion medicine.anatomical_structure Spinal Cord Neurology Female Neurology (clinical) Brainstem business Brain Stem |
| Zdroj: | Annals of Neurology. 11:628-632 |
| ISSN: | 1531-8249 0364-5134 |
| DOI: | 10.1002/ana.410110613 |
| Popis: | A 55-year-old woman presented with rapidly progressive brainstem dysfunction which led to death within a month. She also had constipation for three weeks, and barium enema showed ileus. Subacute encephalomyelitis predominantly involving the medulla and pons correlated with the patient's initial symptoms. In addition, ganglionitis of the myenteric plexuses explained the constipation and ileus. Ganglioradiculoneuropathy was another finding. The presence of abundant neuronophagia in the brainstem, dorsal root ganglia, and myenteric plexuses raised the speculation that a putative virus, toxic agent, or immune reaction possessed special affinity for neurons and ganglion cells. The neuropathological findings were similar to paraneoplastic changes, but no neoplasm was found. |
| Databáze: | OpenAIRE |
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