Afraid to help: Social anxiety partially mediates the association between 5-HTTLPR triallelic genotype and prosocial behavior
| Autor: | Christa C. Christ, Gustavo Carlo, Scott F. Stoltenberg |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Adolescent Genotype Social Psychology media_common.quotation_subject Anxiety Development Altruism Article Developmental psychology Young Adult Behavioral Neuroscience Gene Frequency Escape Reaction Surveys and Questionnaires medicine Humans Allele Social Behavior Association (psychology) Genetic Association Studies Serotonin transporter media_common Serotonin Plasma Membrane Transport Proteins Motivation Polymorphism Genetic biology Negotiating Social anxiety Fear Prosocial behavior 5-HTTLPR biology.protein Regression Analysis Female medicine.symptom Psychology Clinical psychology |
| Zdroj: | Social Neuroscience. 8:400-406 |
| ISSN: | 1747-0927 1747-0919 |
| Popis: | There is growing evidence that the serotonin system influences prosocial behavior. We examined whether anxiety mediated the association between variation in the serotonin transporter gene regulatory region (5-HTTLPR) and prosocial behavior. We collected self-reported tendencies to avoid certain situations and history of helping others using standard instruments and buccal cells for standard 5-HTTLPR genotyping from 398 undergraduate students. Triallelic 5-HTTLPR genotype was significantly associated with prosocial behavior and the effect was partially mediated by social anxiety, such that those carrying the S' allele reported higher levels of social avoidance and lower rates of helping others. These results are consistent with accounts of the role of serotonin on anxiety and prosocial behavior and suggest that targeted efforts to reduce social anxiety in S' allele carriers may enhance prosocial behavior. |
| Databáze: | OpenAIRE |
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