| Autor: |
Xiaotao Chen, Hongwu Xie, Yun Liu, Qiujuan Ou, Shuaijie Deng |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Experimental and therapeutic medicine. 25(1) |
| ISSN: |
1792-1015 |
| Popis: |
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), seriously threatening the health of individuals. The 5-lipoxygenase (ALOX5) gene has been reported to be associated with diabetes, but whether it is involved in DN remains unclear. The present study aimed to explore the role of ALOX5 in DN and to clarify the potential mechanism. Mouse renal mesangial cells (SV40 MES-13) were treated with high glucose (HG) to mimic a DN model |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
