Bio-based composite hydrogels for biomedical applications
| Autor: | Sytze J Buwalda |
|---|---|
| Přispěvatelé: | Centre de Mise en Forme des Matériaux (CEMEF), MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
bio-based polymers
Materials science Biocompatibility Materials Science (miscellaneous) Bio based Nanotechnology 02 engineering and technology fibers 010402 general chemistry 01 natural sciences Nanocellulose [SPI.MAT]Engineering Sciences [physics]/Materials Biomaterials Composite hydrogels Tissue engineering hydrogels Composites chemistry.chemical_classification particles technology industry and agriculture Polymer [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences 021001 nanoscience & nanotechnology 0104 chemical sciences Surfaces Coatings and Films [CHIM.POLY]Chemical Sciences/Polymers chemistry Self-healing hydrogels Biomimetics 0210 nano-technology biomedical. Contents |
| Zdroj: | Multifunctional Materials Multifunctional Materials, IOP Science, 2020, 3 (2), pp.022001. ⟨10.1088/2399-7532/ab80d6⟩ |
| ISSN: | 2399-7532 |
| DOI: | 10.1088/2399-7532/ab80d6⟩ |
| Popis: | International audience; Hydrogels are three-dimensional, water-swollen polymer networks that have been widely studied for biomedical applications such as tissue engineering and the controlled delivery of biologically active agents. Since the pioneering work of Wichterle and Lim in the 1960s, hydrogel research has shifted from relatively simple single polymer networks to multifunctional composite hydrogels that better mimic the complex nature of living tissues. Bio-based polymers, which can be obtained from renewable natural resources, attract increasing attention for use in biomaterials in view of the recent demands for a reduction in the environmental impact of the polymer industry and the development of a sustainable society. Moreover, biobased polymers are often biodegradable and exhibit a significant level of biocompatibility and biomimicry, which are highly desired properties with regard to in vivo application. This review presents the state-of-the-art in the field of bio-based composite hydrogels for biomedical applications, thereby focusing on different types of polymeric components that have been combined with hydrogels to obtain materials with unique, synergistic properties: particles (including micelles and microspheres), electrospun fibres and nanocellulose. In addition, the challenges are described that should be overcome to facilitate clinical application of these versatile and environmentally responsible biomaterials. |
| Databáze: | OpenAIRE |
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