Antimutagenicity of Sweetpotato (Ipomoea batatas) Roots
| Autor: | Masaatu Yamaguchi, Makoto Yoshimoto, Shigenori Okuno, Jiro Yamada, Osamu Yamakawa, Masaru Yoshinaga |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Salmonella typhimurium
Mutant Cyanidin In Vitro Techniques Biology Ipomoea Plant Roots Applied Microbiology and Biotechnology Biochemistry Analytical Chemistry Ames test Anthocyanins chemistry.chemical_compound Pigment Phenols Botany Animals Food science Molecular Biology Chromatography High Pressure Liquid Solanaceae Peonidin Mutagenicity Tests Plant Extracts fungi Organic Chemistry food and beverages Antimutagenic Agents Pigments Biological General Medicine biology.organism_classification Rats chemistry Anthocyanin visual_art visual_art.visual_art_medium Antimutagen Biotechnology |
| Zdroj: | Bioscience, Biotechnology, and Biochemistry. 63:537-541 |
| ISSN: | 1347-6947 0916-8451 |
| DOI: | 10.1271/bbb.63.537 |
| Popis: | Antimutagenicity of the water extracts prepared from the storage roots of four varieties of sweetpotato with different flesh colors was investigated using Salmonella typhimurium TA 98. The extract from the whole roots of the purple-colored Ayamurasaki variety effectively decreased the reverse mutation induced not only by Trp-P-1, Trp-P-2, IQ, B[a]P, and 4-NQO but also by dimethyl sulfoxide extracts of grilled beef. Comparison of the inhibitory activity of the extracts from the normal Ayamurasaki and its anthocyanin-deficient mutant one suggested that the anthocyanin pigment in the flesh decreases the mutagenic activity of the mutagens as heterocyclic amines. Two anthocyanin pigments purified from purple-colored sweet-potato, 3-(6,6'-caffeylferulylsophoroside)-5-glucoside of cyanidin (YGM-3) and peonidin (YGM-6) effectively inhibited the reverse mutation induced by heterocyclic amines, Trp-P-1, Trp-P-2, and IQ in the presence of rat liver microsomal activation systems. |
| Databáze: | OpenAIRE |
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