Exercise, Regardless of Induced Bronchoconstriction or Inspired Air Conditions, Does Not Alter Airway Reactivity
| Autor: | Tracey Webster, Michael Plit, Israel Amirav, Robert Dowdeswell |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Hot Temperature Adolescent Bronchoconstriction Physical Exertion Bronchi Physical exercise Critical Care and Intensive Care Medicine Bronchial Provocation Tests Oxygen Consumption Heart Rate Forced Expiratory Volume Heart rate medicine Humans Child Asthma Breath test medicine.diagnostic_test Inhalation business.industry Air Respiration Humidity medicine.disease Cold Temperature Anesthesia Breathing Female medicine.symptom Cardiology and Cardiovascular Medicine business Airway Histamine |
| Zdroj: | Chest. 104:171-174 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.104.1.171 |
| Popis: | The effects of exercise on asthmatic airway caliber are well recognized. Only a few studies, however, evaluated the effects of prior exercise on asthmatic airway reactivity. Eight asthmatic children (ages 10 to 16 years; mean, 12) performed histamine inhalation tests on three occasions assigned in random order: (1) control; (2) 40 to 60 min after exercise (6 min ergometer cycling) done while breathing cold dry (CD) air (temperature = -13 degrees C, relative humidity = 0 percent); and (3) 40 to 60 min after exercise done while breathing warm humid (WH) air (temperature = 33 degrees C, relative humidity = 100 percent). While there was a marked exercise-induced bronchoconstriction (EIB) in the CD test with a postexercise fall in FEV1 of 39.2 +/- 8 percent (mean +/- SEM), there was no EIB in the WH test (4.6 +/- 2 percent). There was no difference, however, in the geometric mean histamine concentration required to produce a 20 percent fall in FEV1 (PC20) among the CD, WH, and control tests (0.52 mg/ml, 0.60 mg/ml, and 0.55 mg/ml, respectively). Airway reactivity in asthmatic children is not influenced by a prior exercise challenge, independent of the conditions of the inspired air during the exercise. Moreover, exercise per se, regardless of development of EIB, does not change the reactivity. |
| Databáze: | OpenAIRE |
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